Research at the Ludwig Center for Cancer Stem Cell Research and Medicine
The laboratories at the Ludwig Center are engaged in a wide variety of projects to uncover the secrets of cancer stem cells and find cancer therapies.
Irving Weissman, MDMichael Clark, MD
Philip Beachy, PhD
Myelodysplastic Syndrome
Multiple Myeloma
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, and Lymphoma
Role of MicroRNAs in Normal and Malignant Hematopoiesis
Bladder Cancer
Brain Cancer
Melanoma
Epithelial Ovarian Cancer
Identification of Cancer Stem Cells that Contain Low Levels of Reactive Oxygen Species and are Radioresistant
DLL4 Blockade Inhibits Tumor Growth through Multiple Mechanisms Including a Reduction of Cancer Stem Cell Frequency
Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
The Prognostic Role of a Gene Signature from Tumorigenic Breast Cancer Cells
Dysregulated Gene Expression Networks in Human Acute Myelogenous Leukemia Stem CellsDiffuse Intrinsic Pontine Glioma (DIPG)
Anti-Shh/anti-CD47 Combination Therapy in Bladder and Other Epithelial Cancers
Inhibition of Hedgehog Signaling for Treatment of Chronic Myelogenous Leukemia (CML)
Combined Use of Itraconazole and Arsenic Trioxide to Cause Regression of Hh-Dependent Tumors
Research Collaborations:
Ludwig Center scientists at Stanford are actively involved in collaborative research with other Ludwig Centers across the nation:
The Fred Hutchinson Cancer Research Center (Seattle)
Harvard Medical School (Boston)
Memorial Sloan-Kettering Cancer Center (New York)